safewords
For me, part of the fun in tickling is the absolute control I have that no matter how she reacts, the tickling only stops when I sense it has stopped being fun, at least at some level, for her. At no time should safe words be ignored. The moment trust is replaced by panic, all tickling would be stopped in this house, and right now.
Luckily, for us there has been an evolution in our tickling. We pretty much got away from safe words and non-reflex type limits in our late twenties or early thirties. The only way she can get me to stop is when when her tickle reflexes make the pitch of her screaming drop the right amount. She also can convince me when her facial muscles cause her smile or the shape of her eyes to distort slightly into a more tortured look. I've never told her this, so she keeps begging and screaming and whatever else she can do in her efforts.
Silent laughter makes this unbelieveably more fun because she somehow has to get in some air if she is going to even change the pitch of her screams. Then, she often laughs when she should have screamed so she has to go through at least one more laugh cycle to get to where she has a chance again. Eventually, she manages to make me understand.
Now I know I'm not really hurting her. Her silent laughing rarely goes over eight or ten seconds. My guess is this is true for most extremely ticklish people. This is way short of the time necessary to really harm someone with tickling. In fact, it might seem longer for the ticklee, but that just makes the teasing better.
The point is, our methods evolved and the durations between little rests for her became longer and longer over many ticklings. She still tries everything she can to protect herself. Yet she's learned by many repititions that it will stop when it starts to torture her, even if she doesn't have any voluntary control over exactly when that will be. Panic can be a form of torture. Let her build up to it. Heck, your tickle sessions might even last longer if you give her lots of rest periods. You might even find it's fun to tease her to distraction by telling her what you are going to do to her next.
Hiram