Basicaly, the guy here, Embrio , is the resident "God" and has got all the allys he needed by appeling to their weaknesses (loneliness, wishes to save someone, love, etc), since resident badass Ange has shown to be inmune to his charms, he decides to literally mental rape her into submission, his powers allow him to overload his nervious sistem at his wish so he can make her fell pain augmented 50 times, transform all his feelings into pleasure, and in this case make her feel xtreme tickles out of nowhere.
Has a note he alternated all this in what probably was hours in order to break her, and even then she still fliped him the middle finger.